Document Report Card

ID: ALA1150621

Journal: J Nat Prod

Title: Two new triterpenoids from Azadirachta indica and their insecticidal activity.

Authors: Siddiqui BS, Afshan F, Faizi S, Naeem-Ul-Hassan Naqvi S, Tariq RM.

Abstract: Two new triterpenoids, 22,23-dihydronimocinol (1) and desfurano-6alpha-hydroxyazadiradione (2), were isolated from a methanolic extract of the fresh leaves of Azadirachta indica (neem) along with a known meliacin, 7alpha-senecioyl-(7-deacetyl)-23-O-methylnimocinolide. The structures of 1 and 2 were elucidated through spectral and chemical studies. Compounds 1 and 2 showed mortality for fourth instar larvae of the mosquito (Anopheles stephensi), with LC(50) values of 60 and 43 ppm, respectively.

CiteXplore: 12193038

DOI: 10.1021/np0105477