New cytotoxic isomalabaricane triterpenes from the sponge Jaspis species.

ID: ALA1150805

Journal: J Nat Prod

Title: New cytotoxic isomalabaricane triterpenes from the sponge Jaspis species.

Authors: Meragelman KM, McKee TC, Boyd MR.

Abstract: Three new isomalabaricane triterpenes, 29-hydroxystelliferin E (1), 29-hydroxystelliferin A (2), and stelliferin G (3), together with the known triterpene 3-epi-29-hydroxystelliferin E (4), were isolated from the organic extract of the sponge Jaspis sp. collected in the South Pacific. All the compounds isolated showed antiproliferative activity against melanoma cells (MALME-3M).

CiteXplore: 11277766

DOI: 10.1021/np000478g

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