Novel halogenated metabolites from the Malaysian Laurencia pannosa.

Basic Information

ID: ALA1150834

Journal: J Nat Prod

Title: Novel halogenated metabolites from the Malaysian Laurencia pannosa.

Authors: Suzuki M, Daitoh M, Vairappan CS, Abe T, Masuda M.

Abstract: In connection with our chemotaxonomic studies of Malaysian species of the red algal genus Laurencia, the chemical composition of Laurencia pannosa Zanardini was examined. Two halogenated sesquiterpenoids, named pannosanol (1) and pannosane (2), have been isolated along with a halogenated C15-acetogenin, (3Z)-chlorofucin (3). The structures of these compounds were determined from their spectroscopic data (IR, 1H NMR, 13C NMR, 2D NMR, and MS). Pannosanol and pannosane are novel halometabolites with an unusual rearranged chamigrane framework. Antibacterial activities of these metabolites against marine bacteria are also described.

CiteXplore: 11374951

DOI: 10.1021/np0006317

Patent ID: