Document Report Card

ID: ALA1150845

Journal: J Nat Prod

Title: Two new constituents of Isodon excisus and their evaluation in an apoptosis inhibition assay.

Authors: Lee C, Kim J, Lee H, Lee S, Kho Y.

Abstract: Investigation of the whole plant of Isodon excisus resulted in the isolation of two new apoptosis inhibitors (1 and 2). Compounds 1 and 2 inhibited etoposide-induced apoptosis in U937 cells with IC50 values of 10.2 and 52.4 microg/mL, respectively. The structures of 1 and 2 were determined by spectral data interpretation.

CiteXplore: 11374970

DOI: 10.1021/np000604g