Document Report Card

ID: ALA1150853

Journal: J Nat Prod

Title: A new dehydrogeranylgeraniol antioxidant from Saururus cernuus that inhibits intracellular reactive oxygen species (ROS)-catalyzed oxidation within HL-60 cells.

Authors: Rajbhandari I, Takamatsu S, Nagle DG.

Abstract: A new triene, 12,13-dehydrogeranylgeraniol (1), was isolated from the aquatic plant Saururus cernuus and its structure determined spectroscopically. Compound 1 inhibits PMA-induced peroxide-catalyzed oxidation of 2',7'-dichlorodihydrofluorescein dye (DCFH) by reactive oxygen species (ROS) within human promyelocyctic HL-60 cells.

CiteXplore: 11421725

DOI: 10.1021/np0101346