Trichoflectin, a bioactive azaphilone from the ascomycete Trichopezizella nidulus.

ID: ALA1150870

Journal: J Nat Prod

Title: Trichoflectin, a bioactive azaphilone from the ascomycete Trichopezizella nidulus.

Authors: Thines E, Anke H, Sterner O.

Abstract: Trichoflectin (1), a new azaphilone belonging to the deflectin series, 6-deoxy-7-0-demethyl-3,4-anhydrofusarubin (2), and 6-deoxy-3,4-anhydrofusarubin (3) were isolated from submerged cultures of the ascomycete Trichopezizella nidulus. All compounds showed antimicrobial activity and inhibited dihydroxynaphthalene melanin biosynthesis in fungi. The structure of trichoflectin (1) was elucidated by spectroscopic methods.

CiteXplore: 9548866

DOI: 10.1021/np970469g

Patent ID: ┄