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ID: ALA1151141

Journal: J Nat Prod

Title: Antineoplastic agents, 162. Zephyranthes candida.

Authors: Pettit GR, Cragg GM, Singh SB, Duke JA, Doubek DL.

Abstract: The Chinese medicinal plant Zephyranthes candida was found to contain a cytostatic constituent. Separation of a n-BuOH extract directed by results of a bioassay employing the P-388 lymphocytic leukemia led to trans-dihydronarciclasine [2] as the principal cytostatic agent with ED50 3.2 X 10(-3) micrograms/ml.

CiteXplore: 2348199

DOI: 10.1021/np50067a026