A new dimension to the biosynthetic products isolated from the sponge Negombata magnifica.

Basic Information

ID: ALA1151240

Journal: J Nat Prod

Title: A new dimension to the biosynthetic products isolated from the sponge Negombata magnifica.

Authors: Vilozny B, Amagata T, Mooberry SL, Crews P.

Abstract: Latrunculeic acid (3), a novel analogue of latrunculin B (2a), was isolated from the Red Sea sponge Negombata magnifica and characterized. Several known compounds were also isolated, including latrunculin B (2a), 15-methoxylatrunculin B (2b), 16-epi-latrunculin B (4), and latrunculin C (5). In contrast to the other members of the latrunculin family, the novel compound 3 is a polyketide devoid of the normal macrocyclic and thiazolidinone rings present in previously identified members of this family.

CiteXplore: 15217296

DOI: 10.1021/np0340753

Patent ID: