Basic Information
ID: ALA1151929
Journal: Bioorg Med Chem
Title: Synthesis and antiviral activity evaluation of acyclic 2'-azanucleosides bearing a phosphonomethoxy function in the side chain.
Authors: Koszytkowska-Stawińska M, De Clercq E, Balzarini J.
Abstract: Acyclic 2'-azanucleosides with a phosphonomethoxy function in the side chain were obtained by coupling of diethyl {2-[N-(pivaloyloxymethyl)-N-(p-toluenesulfonyl)amino]ethoxymethyl}phosphonate with the pyrimidine nucleobases via the Vorbrüggen-type protocol. The compounds were evaluated in vitro for activity against a broad variety of RNA and DNA viruses.
CiteXplore: 19442526
DOI: 10.1016/j.bmc.2009.04.054
Patent ID: ┄
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