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ID: ALA1152233
Journal: Bioorg Med Chem Lett
Title: The identification of pyrazolo[1,5-a]pyridines as potent p38 kinase inhibitors.
Authors: Cheung M, Harris PA, Badiang JG, Peckham GE, Chamberlain SD, Alberti MJ, Jung DK, Harris SS, Bramson NH, Epperly AH, Stimpson SA, Peel MR.
Abstract: A series of pyrazolo[1,5-a]pyridine derivatives was designed and synthesized as novel potent p38 kinase inhibitors. Our approaches towards improving in vitro metabolism and in vivo pharmacokinetic properties of the series are described.
CiteXplore: 18818075