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ID: ALA1152359

Journal: Bioorg Med Chem Lett

Title: Synthesis and structure-activity relationships of gamma-carboline derivatives as potent and selective cysLT(1) antagonists.

Authors: Bonjoch J, Diaba F, Pagès L, Pérez D, Soca L, Miralpeix M, Vilella D, Anton P, Puig C.

Abstract: A gamma-carboline series of cysLT(1) receptor antagonists has been prepared. Some of the compounds show good potencies both, in vitro and in vivo, compared to the standard compounds.

CiteXplore: 19505824

DOI: 10.1016/j.bmcl.2009.05.094