Document Report Card

Basic Information

ID: ALA1152699

Journal: Bioorg Med Chem

Title: Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens.

Authors: Bassoli A, Borgonovo G, Caimi S, Scaglioni L, Morini G, Moriello AS, Di Marzo V, De Petrocellis L.

Abstract: Perilla frutescens is a food plant widely used in Asian cuisine. This plant was investigated for its interesting taste and somatosensory properties. Perillaldehyde and perillaketone are among the components of the aromatic extracts from P. Frutescens. These compounds were shown here to activate the cloned TRPA1 channel when expressed in an heterologous cell system and are therefore suggested to be responsible for the chemesthetic properties of this plant.

CiteXplore: 19162486

DOI: 10.1016/j.bmc.2008.12.057