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ID: ALA1153059

Journal: Bioorg Med Chem Lett

Title: Novel inhibitors of the alphavbeta3 integrin--lead identification strategy.

Authors: Elliot D, Henshaw E, MacFaul PA, Morley AD, Newham P, Oldham K, Page K, Rankine N, Sharpe P, Ting A, Wood CM.

Abstract: A novel approach to inhibition of the alphavbeta3 integrin is described, which uses compounds designed to generate nM potency without using the arginine binding site.

CiteXplore: 19574045

DOI: 10.1016/j.bmcl.2009.06.041