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ID: ALA1153125
Journal: Bioorg Med Chem Lett
Title: Benzylidene cyclopentenediones: First irreversible inhibitors against botulinum neurotoxin A's zinc endopeptidase.
Authors: Capková K, Hixon MS, Pellett S, Barbieri JT, Johnson EA, Janda KD.
Abstract: A series of benzylidene cyclopentenedione-based inhibitors, acting through covalent modification of the active site of botulinum neurotoxin A light chain metalloprotease, are reported.
CiteXplore: 19914829