Document Report Card
Basic Information
ID: ALA1153228
Journal: Bioorg Med Chem Lett
Title: Synthesis and in vivo evaluation of bicyclic gababutins.
Authors: Blakemore DC, Bryans JS, Carnell P, Carr CL, Chessum NE, Field MJ, Kinsella N, Osborne SA, Warren AN, Williams SC.
Abstract: Synthesis of a number of bicyclic five-membered ring derivatives of gabapentin led to the identification of two compounds, (-)-(11A) and (20A) which both had an excellent level of potency against alpha(2)delta and were profiled in an in vivo model of neuropathic pain.
CiteXplore: 20005103