Document Report Card

ID: ALA1153560

Journal: Antimicrob Agents Chemother

Title: In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds.

Authors: Goldstein EJ, Citron DM, Merriam CV, Warren YA, Tyrrell KL, Fernandez HT.

Abstract: Against 182 anaerobe and 241 aerobe strains obtained from diabetic foot infections, doripenem was the most active carbapenem against Pseudomonas aeruginosa (MIC(90), 2 microg/ml), more active than imipenem against Proteus mirabilis, and ertapenem was more active against Escherichia coli and Klebsiella spp. The MIC(50) and MIC(90) values were < or =0.125 microg/ml for methicillin-sensitive Staphylococcus aureus and all streptococci and 0.25/1 for Bacteroides fragilis.

CiteXplore: 18070958

DOI: 10.1128/aac.01128-07