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ID: ALA1153601
Journal: Bioorg Med Chem Lett
Title: Rapid identification of improved protein ligands using peptoid microarrays.
Authors: Lim HS, Reddy MM, Xiao X, Wilson J, Wilson R, Connell S, Kodadek T.
Abstract: A rapid array-based protocol is presented by which a modest affinity protein-binding small molecule can be appended to a library of peptoids via click chemistry. The array can then be screened for improved ligands that exhibit a higher affinity for the protein target.
CiteXplore: 19380225