Document Report Card

ID: ALA1153834

Journal: Antimicrob Agents Chemother

Title: Orally administered combined regimens for treatment of Mycobacterium ulcerans infection in mice.

Authors: Ji B, Chauffour A, Robert J, Lefrançois S, Jarlier V.

Abstract: Eight weeks of treatment with rifampin-streptomycin sterilizes Mycobacterium ulcerans infection in mice. Because the bactericidal activity against M. ulcerans of the combination rifampin-moxifloxacin, rifampin-clarithromycin, or moxifloxacin-clarithromycin was similar to that of rifampin-streptomycin, these combinations might be considered as alternative, orally administered combined regimens for treatment of Buruli ulcer in humans.

CiteXplore: 17664316

DOI: 10.1128/aac.00730-07