Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine.
Basic Information
ID: ALA1153842
Journal: Antimicrob Agents Chemother
Title: Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine.
Authors: Loup C, Lelièvre J, Benoit-Vical F, Meunier B.
Abstract: Trioxaquines, potential antimalarial agents, and heme-artemisinin adducts, resulting from the alkylation of heme by artemisinin, were evaluated as inhibitors of beta-hematin formation in 10 M acetate medium at pH 5.
CiteXplore: 17698628
DOI: 10.1128/aac.00239-07
Patent ID: ┄
Associated Items: Associated Bioactivities Associated Assays Associated Compounds Associated Targets