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ID: ALA1154101
Journal: Bioorg Med Chem
Title: Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening.
Authors: Gunosewoyo H, Coster MJ, Bennett MR, Kassiou M.
Abstract: The purinergic P2X(7) receptor is a unique member of the ATP-gated P2X family. This receptor has been implicated in numerous diseases and many structurally diverse ligands have been discovered via high throughput screening. This perspective will attempt to highlight some of the most recent key findings in both the biology and chemistry.
CiteXplore: 19540765