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ID: ALA1154170
Journal: Bioorg Med Chem Lett
Title: 2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2.
Authors: Mecinović J, Loenarz C, Chowdhury R, Schofield CJ.
Abstract: Analogues of the 2-oxoglutarate cosubstrate of the human oxygen sensing enzyme prolyl hydroxylase domain 2 (PHD2) with variations in the potential iron-chelating group were screened as inhibitors and for binding (using non-denaturing electrospray ionization mass spectrometry) to PHD2.
CiteXplore: 19775891