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ID: ALA1154368

Journal: Bioorg Med Chem Lett

Title: Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors.

Authors: Yin Y, Lin L, Ruiz C, Cameron MD, Pocas J, Grant W, Schröter T, Chen W, Duckett D, Schürer S, Lograsso P, Feng Y.

Abstract: A series of benzothiazole derivatives as ROCK inhibitors have been discovered. Compounds with good biochemical and cellular potency, and sufficient kinase selectivity have been identified.

CiteXplore: 19837589

DOI: 10.1016/j.bmcl.2009.09.115