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ID: ALA1154510
Journal: Bioorg Med Chem
Title: A new antiangiogenic C24 oxylipin from the soft coral Sinularia numerosa.
Authors: Yamashita T, Nakao Y, Matsunaga S, Oikawa T, Imahara Y, Fusetani N.
Abstract: A new oxylipin, 15-hydroxy-tetracosa-6,9,12,16,18-pentaenoic acid (15-HTPE; 1) was isolated as an inhibitor of tube-formation from the soft coral Sinularia numerosa. Its structure was elucidated by means of spectral analysis and chemical degradation. 15-HTPE inhibited tube formation of EA.hy926 cells at the concentration of 20-40 microM.
CiteXplore: 19036594