Document Report Card

ID: ALA1154563

Journal: J Nat Prod

Title: Flavonol-cinnamate cycloadducts and diamide derivatives from Aglaia laxiflora.

Authors: Xu YJ, Wu XH, Tan BK, Lai YH, Vittal JJ, Imiyabir Z, Madani L, Khozirah KS, Goh SH.

Abstract: Leaf extracts of the Malaysian plant Aglaia laxiflora provided two cytotoxic compounds, a new rocaglaol rhamnoside (1), a known rocaglaol (2), new (but inactive) flavonol-cinnamaminopyrrolidine adducts (3-6), and their probable biosynthetic precursors (7 and trimethoxyflavonol). All structures were elucidated primarily by 2D NMR spectroscopy. The structure and stereochemistry of aglaxiflorin A (3) were confirmed by single-crystal X-ray crystallography.

CiteXplore: 10785416

DOI: 10.1021/np990454d