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ID: ALA1155202
Journal: Bioorg Med Chem Lett
Title: Synthesis and anticancer activity of novel 3,4-diarylthiazol-2(3H)-ones (imines).
Authors: Liu ZY, Wang YM, Li ZR, Jiang JD, Boykin DW.
Abstract: A series of 3,4-diarylthiazol-2(3H)-ones and three 3,4-diarylthiazol-2(3H)-imines were synthesized and evaluated for their cytotoxicity in a panel of human cancer cell lines. Compounds 21 and 22 showed potential anticancer activity against human CEM cells with IC50 values of 0.12 and 0.24microM, respectively.
CiteXplore: 19713108