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ID: ALA1155246

Journal: Bioorg Med Chem

Title: Synthesis, antioxidant properties and radioprotective effects of new benzothiazoles and thiadiazoles.

Authors: Cressier D, Prouillac C, Hernandez P, Amourette C, Diserbo M, Lion C, Rima G.

Abstract: In this work, we report the synthesis and characterization of new compounds derived from benzothiazoles and thiadiazoles. We observed that structural modifications on these skeletons affected the antioxidant activity. Thiol and aminothiol compounds derived from thiadiazoles and benzothiazoles showed an interesting antioxidant property. The radioprotective activity has also been evaluated in mice. Some of these compounds could be good radioprotectors.

CiteXplore: 19502068

DOI: 10.1016/j.bmc.2009.05.039