Thiazole analog as stearoyl-CoA desaturase 1 inhibitor.

ID: ALA1155314

Journal: Bioorg Med Chem Lett

Title: Thiazole analog as stearoyl-CoA desaturase 1 inhibitor.

Authors: Li CS, Belair L, Guay J, Murgasva R, Sturkenboom W, Ramtohul YK, Zhang L, Huang Z.

Abstract: SCD1 inhibition may represent a novel treatment for obesity, type-2 diabetes and related metabolic disorders. A prototype thiazole amide analog 13 (MF-152) was identified as an excellent tool in the study of SCD biology in animals.

CiteXplore: 19632834

DOI: 10.1016/j.bmcl.2009.07.015

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