Document Report Card

ID: ALA1155566

Journal: J Nat Prod

Title: Antifeedant activity of withanolides from Salpichroa origanifolia on Musca domestica.

Authors: Mareggiani G, Picollo MI, Zerba E, Burton G, Tettamanzi MC, Benedetti-Doctorovich MO, Veleiro AS.

Abstract: The antifeedant effect of several salpichrolides on larvae of Musca domestica was investigated. Three naturally occurring compounds, salpichrolide A (1), salpichrolide C (2), and salpichrolide G (3), previously isolated from Salpichroa origanifolia, and two known (4, 6) and three new (5, 7, 8) synthetic analogues were tested. The maximal effect on development was observed for salpichrolide A (1), while salpichrolide G (3) was the most toxic. The content of the salpichrolides in S. origanifolia was monitored by HPLC during plant development, reaching a maximum during summer.

CiteXplore: 10978207

DOI: 10.1021/np0001068