Bioactive sesquiterpenes from the basidiomycete Resupinatus leightonii.

ID: ALA1155593

Journal: J Nat Prod

Title: Bioactive sesquiterpenes from the basidiomycete Resupinatus leightonii.

Authors: Eilbert F, Engler-Lohr M, Anke H, Sterner O.

Abstract: 1(10),4-Germacradiene-2,6,12-triol (1), a new germacrane sesquiterpene, and 1,6-farnesadiene-3,10,11-triol (2), a known nerolidol derivative, were isolated from submerged cultures of the basidiomycete Resupinatus leightonii. Both compounds inhibited cAMP-induced appressorium formation in Magnaporthe grisea and showed cytotoxic activity. The structure of 1 was determined by NMR and mass spectroscopic methods.

CiteXplore: 11000039

DOI: 10.1021/np0002031

Patent ID: ┄