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ID: ALA1155626

Journal: J Nat Prod

Title: Metabolites of Colletotrichum gloeosporioides, an endophytic fungus in Artemisia mongolica.

Authors: Zou WX, Meng JC, Lu H, Chen GX, Shi GX, Zhang TY, Tan RX.

Abstract: A new antimicrobial metabolite, named colletotric acid (1), was isolated from a liquid culture of Colletotrichum gloeosporioides, an endophytic fungus colonized inside the stem of Artemisia mongolica. The structure was determined using spectroscopic methods (EIMS and FABMS,(1)H and (13)C NMR, (1)H-(1)H COSY, HMBC, and HMQC). Compound 1 inhibited the growth of Bacillus subtilis, Staphylococcusaureus, and Sarcina lutea with minimal inhibitory concentrations (MICs) of 25, 50, and 50 microg/mL, respectively, and the crop pathogenic fungus Helminthosporium sativum (MIC: 50 microg/mL).

CiteXplore: 11087599

DOI: 10.1021/np000204t