Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1).

Basic Information

ID: ALA1155844

Journal: Bioorg Med Chem Lett

Title: Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1).

Authors: Purandare AV, Chen Z, Huynh T, Pang S, Geng J, Vaccaro W, Poss MA, Oconnell J, Nowak K, Jayaraman L.

Abstract: This study reports the identification and Hits to Leads optimization of inhibitors of coactivator associated arginine methyltransferase (CARM1). Compound 7b is a potent, selective inhibitor of CARM1.

CiteXplore: 18619839

DOI: 10.1016/j.bmcl.2008.06.026

Patent ID: ┄

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