Basic Information
ID: ALA1156394
Journal: J Nat Prod
Title: Low-density lipoprotein-antioxidant constituents of Saururus chinensis.
Authors: Ahn BT, Lee S, Lee SB, Lee ES, Kim JG, Bok SH, Jeong TS.
Abstract: A new diarylbutane lignan, saururin A (1), and a known 8-O-4'-type neolignan, machilin D (2), were isolated from a total methanol extract of the underground parts of Saururus chinensis. The structures of 1 and 2 were elucidated by spectroscopic data analysis. Compounds 1, 2, and virolin (3) (the methyl ether of 2) exhibited significant low-density lipoprotein (LDL)-antioxidant activity in the thiobarbituric acid-reactive substance (TBARS) assay with IC(50) values of 8.5, 2.9, and 4.3 microM, respectively.
CiteXplore: 11754613
DOI: 10.1021/np0006061
Patent ID: ┄
Associated Items: Associated Bioactivities Associated Assays Associated Compounds Associated Targets