Document Report Card

ID: ALA1156640

Journal: J Nat Prod

Title: Cyclopeptides with anti-inflammatory activity from seeds of Annona montana.

Authors: Chuang PH, Hsieh PW, Yang YL, Hua KF, Chang FR, Shiea J, Wu SH, Wu YC.

Abstract: Four new cyclopeptides, cyclomontanins A-D (1- 4), annomuricatin C (5), and (+)-corytuberine were isolated from a methanol extract of Annona montana seeds. Their structures were elucidated by 2D NMR analysis, ESIMS/MS fragment evidence, and chemical means. The structure of 1 was confirmed by synthesis. Compounds 1, 3, and 4 exhibited anti-inflammatory activity in vitro using the J774.1 macrophage model.

CiteXplore: 18687006

DOI: 10.1021/np8001282