Antifungal cyclic depsipeptide, eujavanicin A, isolated from Eupenicillium javanicum.

ID: ALA1156658

Journal: J Nat Prod

Title: Antifungal cyclic depsipeptide, eujavanicin A, isolated from Eupenicillium javanicum.

Authors: Nakadate S, Nozawa K, Sato H, Horie H, Fujii Y, Nagai M, Hosoe T, Kawai K, Yaguchi T.

Abstract: In the course of searching for new antifungal agents, a new cyclic depsipeptide, eujavanicin A (1), was isolated from Eupenicillium javanicum as an antifungal agent against the human pathogenic filamentous fungus Aspergillus fumigatus. The structure of 1 was established by spectroscopic and chemical investigations. The absolute stereochemistry was elucidated by Marfey's method and by chiral HPLC analysis.

CiteXplore: 18771240

DOI: 10.1021/np8002904

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