Tetracyclic terpenoids from Dasyscyphus niveus, dasyscyphins D and E.

ID: ALA1156662

Journal: J Nat Prod

Title: Tetracyclic terpenoids from Dasyscyphus niveus, dasyscyphins D and E.

Authors: Liermann JC, Kolshorn H, Anke H, Thines E, Opatz T.

Abstract: Cultures of the ascomycete Dasyscyphus niveus have yielded two new tetracyclic dasyscyphin-type terpenoids (1 and 2), and their structures were elucidated by NMR spectroscopy and X-ray crystallography. The absolute configuration of dasyscyphin D (1) was determined by synthesis and NMR spectroscopy of diastereomeric MTPA esters. Both compounds inhibited the germination of conidia of Magnaporthe grisea at 25 microg/mL.

CiteXplore: 18771321

DOI: 10.1021/np800355a

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