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ID: ALA1156707
Journal: Eur J Med Chem
Title: Insulin-releasing activity of a series of phenylalanine derivatives.
Authors: Tang L, Yu J, Wu H, Fan H, Yang Y, Ji R.
Abstract: A series of phenylalanine derivatives were synthesized and their biological activities were evaluated. Compounds (S)-3 and (R)-3 exhibited more potent insulin-releasing activity than that of nateglinide, compound (S)-3 also showed insulin-sensitizing activity in vitro. Both compounds were tested for hypoglycemia effect in vivo.
CiteXplore: 18191001