Document Report Card

ID: ALA1157277

Journal: J Nat Prod

Title: Antifungal and antibacterial metabolites from a sclerotium-colonizing isolate of Mortierella vinacea.

Authors: Soman AG, Gloer JB, Wicklow DT.

Abstract: The known compound methyl 2,4-dihydroxy-3,5,6-trimethylbenzoate (1) and three new related metabolites, which we have named mortivinacins A (2), B (3), and C (4), were identified as metabolites of the fungus Mortierella vinacea. Nicotinic acid (5) was also encountered. This isolate of M. vinacea was obtained from an Aspergillus flavus sclerotium during field studies of sclerotium longevity in soil. Compounds 1-5 were isolated by chromatographic fractionation of organic extracts from M. vinacea solid-substrate fermentation cultures, and the structures were assigned by analysis of NMR and MS data. Compounds 1, 2, and 5 were responsible for the antibacterial and antifungal activities of the extract.

CiteXplore: 10075797

DOI: 10.1021/np980411h