Document Report Card

ID: ALA1157318

Journal: J Nat Prod

Title: Caryophyllene sesquiterpenoids from a fungicolous isolate of Pestalotiopsis disseminata.

Authors: Deyrup ST, Swenson DC, Gloer JB, Wicklow DT.

Abstract: Three new caryophyllene-type sesquiterpene alcohols, 6-hydroxypunctaporonin E (1), 6-hydroxypunctaporonin B (2), and 6-hydroxypunctaporonin A (3), have been isolated from cultures of the fungicolous fungus Pestalotiopsis disseminata. The structures of 1-3 were determined mainly by analysis of 1D and 2D NMR data. The structure and absolute configuration of 6-hydroxypunctaporonin E (1) was confirmed through X-ray crystallographic analysis of its mono-bromobenzoate derivative. Compounds 1 and 2 showed activity against Gram-positive bacteria.

CiteXplore: 16643036

DOI: 10.1021/np050460b