Document Report Card

ID: ALA1157383

Journal: J Nat Prod

Title: Antiproliferative oleanane saponins from Meryta denhamii.

Authors: Cioffi G, Dal Piaz F, Vassallo A, Venturella F, De Caprariis P, De Simone F, De Tommasi N.

Abstract: Eight new oleanane saponins (1- 8) together with four know saponins (9-12) were isolated from the aerial parts of Meryta denhamii. Their structures were elucidated by 1D and 2D NMR experiments including 1D TOCSY, DQF-COSY, ROESY, HSQC, and HMBC spectroscopy, as well as ESIMS analysis. The antiproliferative activity of all compounds was evaluated using three murine and human cancer cell lines: J774.A1, HEK-293, and WEHI-164.

CiteXplore: 18442289

DOI: 10.1021/np8000464