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ID: ALA1157667
Journal: Bioorg Med Chem
Title: Synthesis of glycyrrhetinic acid derivatives for the treatment of metabolic diseases.
Authors: Beseda I, Czollner L, Shah PS, Khunt R, Gaware R, Kosma P, Stanetty C, Del Ruiz-Ruiz MC, Amer H, Mereiter K, Da Cunha T, Odermatt A, Classen-Houben D, Jordis U.
Abstract: The effect of glycyrrhetinic acid (GA) and GA-derivatives towards 11beta-hydroxysteroid dehydrogenase (11beta-HSD) was investigated. Novel compounds with modifications at positions C-3, C-11 and C-29 of the GA skeleton were prepared. Single crystal X-ray diffraction data of selected substances are reported and discussed.
CiteXplore: 19914836