Cytotoxic nor-chamigrane and chamigrane endoperoxides from a basidiomycetous fungus.
Basic Information
ID: ALA1157761
Journal: J Nat Prod
Title: Cytotoxic nor-chamigrane and chamigrane endoperoxides from a basidiomycetous fungus.
Authors: Chokpaiboon S, Sommit D, Teerawatananond T, Muangsin N, Bunyapaiboonsri T, Pudhom K.
Abstract: A new nor-chamigrane endoperoxide, merulin A (1), and two new chamigrane endoperoxides, merulins B and C (2, 3), were isolated from the culture broth extract of an endophytic fungus of Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic, mainly NMR and MS, data. X-ray crystallographic analysis confirmed the structure of 1. Compounds 1 and 3 displayed significant cytotoxicity against human breast (BT474) and colon (SW620) cancer cell lines.
CiteXplore: 20411928
DOI: 10.1021/np100103j
Patent ID: ┄