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ID: ALA1157939

Journal: J Nat Prod

Title: Bromophycolides C-I from the Fijian red alga Callophycus serratus.

Authors: Kubanek J, Prusak AC, Snell TW, Giese RA, Fairchild CR, Aalbersberg W, Hay ME.

Abstract: Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines.

CiteXplore: 16724831

DOI: 10.1021/np050463o