Document Report Card

ID: ALA1158006

Journal: J Nat Prod

Title: Alkylfurans: effects of alkyl side-chain length on insecticidal activity.

Authors: Rodriguez-Saona CR, Maynard DF, Phillips S, Trumble JT.

Abstract: The insecticidal activity of five alkylfurans against the generalist insect herbivore beet armyworm, Spodoptera exigua, was examined. Two naturally occurring compounds, the avocadofurans 2-(pentadecyl)furan (1) and 2-(heptadecyl)furan (2), previously isolated from specialized avocado idioblast oil cells, and three homologues, 2-(tetradecyl)furan (3), 2-(hexadecyl)furan (4), and 2-(octadecyl)furan (5), were synthesized. Bioassays of alkylfurans 1-5 using a 9-day diet-incorporation initiated with neonates showed that all alkylfurans tested significantly increased S. exigua larval mortality and reduced larval weights, with maximal biological activity detected among the naturally occurring alkylfurans 1 and 2.

CiteXplore: 9917319

DOI: 10.1021/np980340m