Document Report Card

ID: ALA1158025

Journal: J Nat Prod

Title: Antimalarial activity of macrocyclic trichothecenes isolated from the fungus Myrothecium verrucaria.

Authors: Isaka M, Punya J, Lertwerawat Y, Tanticharoen M, Thebtaranonth Y.

Abstract: Bioassay-guided fractionation of an extract from the fungus Myrothecium verrucaria BCC 112 resulted in the first isolation of roridin E acetate (5) from nature together with four common macrocyclic trichothecene isomers (1-4). Trichothecenes 1-5, while known as mycotoxins, were evaluated for their high antimalarial activity.

CiteXplore: 10075777

DOI: 10.1021/np980323x