Document Report Card

ID: ALA1158139

Journal: J Nat Prod

Title: Bioactive oligostilbenoids from the stem bark of Hopea exalata.

Authors: Ge HM, Huang B, Tan SH, Shi da H, Song YC, Tan RX.

Abstract: Hopeanolin (1), an unusual resveratral trimer with an ortho-quinone nucleus, was isolated and characterized from the stem bark of Hopea exalata. Also obtained were six known stibenoids, shoreaphenol (2), vaticanol G (3), alpha-viniferin (4), pauciflorol A (5), vaticanol A (6), and trans-3,5,4'-trihydroxystilbene 2-C-glucoside (7). The structure of 1 was determined by spectroscopic data interpretation. Compounds 1-7 were tested for antifungal activity and inhibitory effects against jack bean urease. Hopeanolin (1) demonstrated antifungal activity in the MIC value range 0.1-22.5 microg/mL.

CiteXplore: 17190464

DOI: 10.1021/np060242y