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ID: ALA1158144

Journal: J Nat Prod

Title: Cacalol derivatives from Roldana angulifolia.

Authors: Arciniegas A, Pérez-Castorena AL, Villaseñor JL, Romo de Vivar A.

Abstract: Four new modified eremophilanes, angulifolide (1) and angulifolins A-C (2-4), and two new triacetylglucosides (7 and 8) were isolated from Roldana angulifolia, together with several known compounds. The structures of the new compounds were elucidated by spectroscopic analysis and chemical reactions. The absolute configuration of compounds 2 and 3 was established by Mosher ester methodology. Cytotoxicity against selected human cancer cell lines was determined for the more abundant isolated metabolites.

CiteXplore: 17190472

DOI: 10.1021/np0604073