Document Report Card

ID: ALA1158193

Journal: J Nat Prod

Title: Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.

Authors: Lale A, Herbert JM, Augereau JM, Billon M, Leconte M, Gleye J.

Abstract: Sixty-five natural flavonoids of various chemical classes were screened for their ability to inhibit the procoagulant activity of adherent human monocytes stimulated by endotoxin and interleukin-1 beta in vitro. Eighteen of these compounds inhibited the interleukin-1 beta-induced expression of tissue factor on human monocytes, but the most active compound was a biflavonoid: hinokiflavone.

CiteXplore: 8882428

DOI: 10.1021/np960057s