Two new naphthoquinones with antiviral activity from Rhinacanthus nasutus.

ID: ALA1158236

Journal: J Nat Prod

Title: Two new naphthoquinones with antiviral activity from Rhinacanthus nasutus.

Authors: Sendl A, Chen JL, Jolad SD, Stoddart C, Rozhon E, Kernan M, Nanakorn W, Balick M.

Abstract: Two new naphthoquinones, rhinacanthin-C (1) and rhinacanthin-D (2), exhibit inhibitory activity against cytomegalovirus (CMV), with EC50 values of 0.02 and 0.22 microgram/mL, respectively, against human CMV. They were isolated from the medicinal plant Rhinacanthus nasutus (Acanthaceae). The structures of the compounds were determined by analysis of their spectroscopic data, in particular, 2D NMR.

CiteXplore: 8792629

DOI: 10.1021/np9601871

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