Document Report Card

ID: ALA1158672

Journal: J Nat Prod

Title: Rubrobramide, a cytotoxic and phytotoxic metabolite from Cladobotyrum rubrobrunnescens.

Authors: Wagner C, Anke H, Sterner O.

Abstract: Cladobotrin (1) and rubrobramide (2) were isolated from the culture filtrate of Cladobotryum rubrobrunnescens, a mycophilic deuteriomycete. Rubrobramide (2), possessing a unique oxidized tricyclic system, is a new compound structurally related to flavipucine (3), which also is produced by the fungus. The structure of 2 was determined by spectroscopic methods. Cladobotrin (1) exhibited weak nematicidal activity toward Meldogyne incognita, while 2 showed weak cytotoxic and phytotoxic activities.

CiteXplore: 9625624

DOI: 10.1021/np9704967