Constituents of the leaves and twigs of Calyptranthes pallens collected from an experimental plot in Southern Florida.
Basic Information
ID: ALA1158738
Journal: J Nat Prod
Title: Constituents of the leaves and twigs of Calyptranthes pallens collected from an experimental plot in Southern Florida.
Authors: Lobo-Echeverri T, Rivero-Cruz JF, Su BN, Chai HB, Cordell GA, Pezzuto JM, Swanson SM, Soejarto DD, Kinghorn AD.
Abstract: Fractionation of the chloroform-soluble extract of the leaves and twigs of Calyptranthes pallens, collected from an experimental plot in a hardwood forest of southern Florida, using a hormone-dependent human prostate carcinoma (LNCaP) tumor cell line, led to the isolation of a phloroglucinol derivative with a novel carbon skeleton, pallenic acid (1), and a new triterpenoid, 3beta-hydroxy-18alpha,19alpha-urs-20-en-28-oic acid (2). The known compound methylene-bis-aspidinol (3) was selectively active against the human oral epidermoid carcinoma (KB) cell line. Several known compounds of the ellagic acid, lignan, phloroglucinol, sterol, and triterpene types were also obtained in the present investigation.
CiteXplore: 15844953
DOI: 10.1021/np0496688
Patent ID: ┄